Signs of Canine Cognitive Dysfunction: Could It Affect Your Dog?

Behavioral changes can be signs of Canine Cognitive Dysfunction (CCD). Learn how to recognize it, and how a combination of conventional and alternative therapies can help treat it.

Does your dog ever show signs of disorientation or anxiety? Does he seem lost, or have more accidents in the house? He may have canine cognitive dysfunction (CCD), a condition that mirrors the cognitive decline seen in humans with dementia, specifically Alzheimer’s disease. This article will help you recognize the signs of Canine Cognitive Dysfunction, understand why it occurs, and explore how an integrative approach can help both treat and prevent it.

Causes and prevalence of CCD

Canine Cognitive Dysfunction arises from the accumulation of neurotoxic proteins in the dog’s brain. This leads to the formation of plaques and, in turn, impaired cognitive function.

The risk of developing canine cognitive dysfunction increases as dogs get older, with signs of cognitive decline potentially appearing as early as six years of age. Larger breeds tend to show symptoms earlier than smaller breeds, but the occurrence of CCD varies across all dogs, with differences in onset, progression, and severity.

Signs and symptoms 

The behavioral and cognitive changes associated with CCD can profoundly affect a dog’s quality of life. Symptoms include:

  • Disorientation
  • Sleep-wake cycle disturbances
  • Altered social interactions
  • Incontinence
  • Changes in activity level
  • Aggression
  • Decreased interest in play
  • Impaired learning and memory
  • Repetitive behavior
  • Aimless wandering

These signs not only signal a decline in the dog’s cognitive abilities, but also pose challenges for families in managing daily needs and maintaining a healthy human-animal bond.

An integrative treatment approach to CCD

A combination of management strategies, medications, dietary changes, and environmental enrichment can slow the progression of canine cognitive dysfunction and improve the affected dog’s quality of life. This integrative approach encompasses both traditional and alternative treatments.

  1. Dietary changes and supplements: Nutritional interventions play a crucial role in managing CCD. Healthy diets rich in antioxidants, Omega-3 fatty acids, medium-chain triglycerides (MCTs), and specific vitamins and minerals may support brain health and slow cognitive decline. Supplements such as S-adenosylmethionine (SAMe), phosphatidylserine, and certain phytochemicals like curcumin have shown promise in clinical studies.
  1. Chinese herbal therapy: Traditional Chinese Medicine, including the use of herbs like ginkgo biloba and ginseng, supports cognitive function in dogs with CCD. These treatments have gained attention for their potential to address cognitive impairment. “In my clinical practice, I’ve found remarkable success treating CCD by integrating conventional nutraceuticals with Chinese herbal supplements,” says Dr. Curtis Dewey, a renowned veterinary neurologist.
  1. Medications: On the conventional side, drugs such as selegiline, a monoamine oxidase inhibitor, aim to mitigate symptoms and enhance the dog’s cognitive abilities.

Preventive measures and slowing progression

Prevention serves as the best defense against canine cognitive dysfunction. Interventions focus on delaying the onset of cognitive decline.

  • Maintaining proper dental care in your dog from an early age ranks as one of the best prevention tactics — research shows a relationship between periodontal disease/inflammation and cognitive decline in dogs.
  • Other strategies include engaging your dog in regular physical exercise, social interactions, cognitive training, and dietary management from middle age onwards.
  • The use of preventive supplements as outlined above, along with environmental enrichment (see below) and regular veterinary check-ups will help maintain your dog’s cognitive health and identify early signs of CCD.

Environmental enrichment strategies

In addition to medical interventions, environmental enrichment and lifestyle modifications play vital roles. Engaging your dog in mentally stimulating activities, such as puzzle toys, scent games, and interactive play, can enhance cognitive function and overall well-being. Tailoring these activities to your individual dog’s preferences and abilities keeps your furry friend engaged and mentally active.

A comprehensive approach to CCD works best

Understanding and managing canine cognitive dysfunction requires a comprehensive approach that addresses the physiological, emotional, and environmental needs of the aging dog. By being aware of the signs of canine cognitive dysfunction, you can work with your veterinarian to improve your dog’s quality of life. Early detection, individualized care, and ongoing support of the canine-human bond all remain crucial when navigating the challenges of cognitive decline. If your dog is ever affected by CCD, you and your veterinarian can work together to improve his quality of life by understanding its parallels to human dementia, recognizing the signs and symptoms, and implementing a combination of integrative treatment and preventive strategies.

How CCD compares with Alzheimer’s 

The striking parallels between CCD and Alzheimer’s disease in humans provide a framework for understanding how cognitive decline manifests across species. Both conditions involve the buildup of similar neurotoxic proteins that disrupt normal brain function.

Despite these similarities, there are notable differences in the progression and impact of the disease in both species. Dogs with CCD often experience a milder form of cognitive dysfunction compared to the often debilitating progression observed in humans with Alzheimer’s. This difference suggests that while the underlying pathological processes share similarities, the expression and outcome of the disease can vary significantly between dogs and humans. The good news is that dogs respond well to treatment.

See the vet

Keep in mind that many symptoms of canine cognitive dysfunction can also signal other conditions. It’s always important to have your dog checked out by your veterinarian when and if you notice any changes in his behavior.

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Theresa W. Fossum, D.V.M., M.S., Ph.D., DACVS is currently CEO of Epic Veterinary Specialists and CEO and Co-Founder at Dr. Fossum’s Pet Care.

Dr. Fossum was previously the Vice President of Research and Strategic Initiatives and a Professor of Veterinary Surgery at Midwestern University. Dr. Fossum is responsible for overseeing the development of the Midwestern University Institute for Healthcare Innovation (IHI) including but not limited to clinical trials, new research funding programs and related work that impacts the One Health philosophy of Midwestern University.

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